Human Biology Aging and Death in an Organism

Discussion in 'Human Biology' started by mscbkc070904, Apr 5, 2005.

  1. mscbkc070904

    mscbkc070904 Premium Member

    In macroscopic organisms, aging is often obvious; in single-celled organisms, where there is the greatest potential to identify the molecular mechanisms involved, identifying and quantifying aging is harder. The primary results in this area have come from organisms that share the traits of a visibly asymmetric division and an identifiable juvenile phase. As reproductive aging must require a differential distribution of aged and young components between parent and offspring, it has been postulated that organisms without these traits do not age, thus exhibiting functional immortality. Through automated time-lapse microscopy, we followed repeated cycles of reproduction by individual cells of the model organism Escherichia coli, which reproduces without a juvenile phase and with an apparently symmetric division. We show that the cell that inherits the old pole exhibits a diminished growth rate, decreased offspring production, and an increased incidence of death. We conclude that the two supposedly identical cells produced during cell division are functionally asymmetric; the old pole cell should be considered an aging parent repeatedly producing rejuvenated offspring. These results suggest that no life strategy is immune to the effects of aging, and therefore immortality may be either too costly or mechanistically impossible in natural organisms.

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  2. bodebliss

    bodebliss The Zoc-La of Kromm-B Premium Member

    I see what your saying, but do not discount the ingenuity of humans, if they want it will be.
  3. xu

    xu Premium Member

    we must upgrade the fueling system I guess, because the aging is caused by oxygen, which also gives us life kills us slowly, like the corrosion on metals, oxygen damages the cells in a way when it is burned to create energy.
  4. bodebliss

    bodebliss The Zoc-La of Kromm-B Premium Member


    there is a move afoot to find a way to tuck mitochondrion DNA into the nucleus of the cell and thus protect and preserve it.

    There is research going forward on the cell's antioxidant mechanism. Mostly centered around extra DNA sequences(Let's say your DNA has 1 sequence for these 2 antioxidants. They will insert more sequences so your cells become full of antioxidants) to express the peptide methionine sulfoxide reductase A & B which will undo the damage done to the cell by the oxidation of proteins.

    As to the article I am sure it will cause a great deal of discussion in some circles, but that is the beginning of solutions.